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Table 4 Factors associated with mortality by logistic regression

From: Appropriateness of empiric antimicrobial therapy with imipenem/colistin in severe septic patients: observational cohort study

Varieties Survivors (n = 46) Died (n = 33) OR [95% CI] p
Inappropriate EAMT, n (%) 18 (39%) 20 (61%) 6.27 [1.83–21] 0.003
Age, mean ± DSa 52 ± 18 54 ± 16 1.15 [0.28–4.64] 0.83
SOFAa, mean ± DS 5.52 6.36 1.58 [0.79–2.91] 0.37
Chronic respiratory failure, n (%) 16 (35%) 11 (33%) 0.87 [0.35–2.15] 0.77
Cardiovascular disease, n (%) 19 (41%) 22 (66%) 1.43 [0.56–2.79] 0.25
Diabetes, n (%) 19 (41%) 12 (36%) 0.77 [0.27–1.96] 0.48
ICU acquired NI, n (%) 8 (17%) 15 (45%) 2.02 [1.37–12.12] 0.044
ED acquired NI, n (%) 20 (43%) 17 (51%) 1.16 [0.65–3.37] 0.67
Medical service acquired NI, n (%) 9 (19%) 4 (12%) 0.62 [0.01–1.84] 0.13
Shock, n (%) 11 (24%) 21 (63%) 1.96 [0.87–9.28] 0.09
  1. EAMT, empiric antimicrobial therapy; SOFA, Sequential Organ Failure Assessment; ICU, intensive care unit; ED, emergency department; NI, nosocomial infection; OR, odds ratio; CI, confidence interval
  2. aStudied variables: age > 50 years and SOFA > 5
  3. Italic values indicate p < 0.05