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Etiology
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DOT (days)
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DDD
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|---|
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Median (IQR)
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Median (IQR)
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|---|
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Gram+ N = 452
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Aminoglycosides
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7.0 (5.0; 9.0)
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0.109 (0.560; 0.180)
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Antimycotics
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12.0 (9.3; 16.0)
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0.195 (0.131; 0.341)
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|
Beta-lactams
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7.0 (5.0; 10.0)
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0.252 (0.180; 0.420)
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|
Glycopeptides
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10.0 (8.0; 11.0)
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0.128 (0.088; 0.168)
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Other
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9.0 (5.0; 15.0)
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0.211 (0.096; 0.452)
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Total
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9.0 (5.0; 15.0)
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0.140 (0.056; 0.453)
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Gram− N = 103
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Aminoglycosides
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6.0 (4.3; 8.0)
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0.056 (0.036; 0.137)
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Antimycotics
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12.0 (8.2; 17.0)
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0.228 (0.131; 0.360)
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Beta-lactams
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8.0 (4.0; 11.0)
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0.244 (0.096; 0.448)
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Glycopeptides
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8.0 (4.0; 9.0)
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0.098 (0.039; 0.149)
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Other
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8.5 (5.3; 10.8)
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0.229 (0.099; 0.608)
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Total
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7.5 (4.0; 17.0)
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0.136 (0.036; 0.447)
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Changing N = 76
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Aminoglycosides
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7.0 (5.0; 10.0)
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0.105 (0.061; 0.180)
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Antimycotics
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12.0 (10.0; 16.0)
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0.250 (0.158; 0.735)
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Beta-lactams
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7.0 (6.5; 11.0)
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0.281 (0.169; 0.495)
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Glycopeptides
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10.0 (7.0; 11.0)
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0.085 (0.056; 0.167)
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Other
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9.0 (6.0; 14.5)
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0.187 (0.120; 2.580)
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Total
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9.0 (5.0; 16.0)
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0.149 (0.056; 2.580)
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Candida N = 18
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Aminoglycosides
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8.5 (4.8; 12.8)
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0.140 (0.070; 0.210)
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Antimycotics
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10.5 (9.0; 15.8)
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0.225 (0.092; 0.353)
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Beta-lactams
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12.0 (9.0; 19.5)
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450 (192.9; 2175)
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Glycopeptides
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10.0 (7.3; 10.8)
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0.087 (0.063; 0.161)
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Other
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13.5 (10.0; 17.0)
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3.276 (0.153; 6.400)
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Total
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10.0 (4.8; 19.5)
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0.164 (0.063; 6.400)
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- Changing—when, during treatment, positive microbiological cultures were obtained from different samples, or samples taken at different times (within 5 days), growth of microorganisms belonging to various groups (e.g. Escherichia coli and Candida albicans) was defined as cases of changing etiology (group “changing”)
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DOT days of therapy (per one case), DDD defined daily dose (per one case), IQR interquartile range, N number of cases
